In vitro simulated digestive system SHIME is widely used in gut microbiota laboratories and nutrition laboratories of universities, research institutes, and enterprises. It is an ideal tool for in vitro gut model SHIME experiments, including batch culture models, continuous fermentation culture systems (ascending colon, transverse colon, and descending colon), and human gut microbiota simulators (stomach, duodenum, small intestine, ascending colon, transverse colon, descending colon).

The main functions of the in vitro digestion simulation system for monogastric animals (six parts stomach duodenum small intestine ascending colon transverse colon descending colon) are:

1. Control the constant temperature of the gastrointestinal tract; Temperature can be controlled between 30-40 ℃; Accuracy: ± 0.1 ℃; Intelligent PID temperature control; Adopting a brand new semiconductor waterless temperature control system;

2. Control the physical and chemical environment in the gastrointestinal tract; Peristalsis, acidity, slight positive pressure, anaerobic environment;

3. Automatically detect and control the acidity of different simulated parts;

4. Perform enzymatic hydrolysis reaction and simulate the secretion of digestive enzymes in the gastrointestinal tract;

5. Detecting the chemical changes in "food" during the digestion process;

6. Simulate small intestine endocrine digestive enzymes to further digest and degrade substrates; At the same time, provide an environment for the growth of various microorganisms in the gastrointestinal tract of monogastric animals;

7. Simulate multiple absorption methods and perform active and passive absorption based on the absorption characteristics of different parts;

8. The secretion volume and rate of digestive and secretion fluids can be regulated within the range of 0-150ml/min; Parameters can be set and modified by oneself;

9. The experimental repetition rate deviation is less than 1%; Absorption deviation<2%;

10. Easy to operate and assemble, the program can automatically analyze data and draw curves, and the system comes with multiple simulated process formulas;

11. The server adopts WFC remote communication mode;

12. The client development adopts Siemens programmable on-site control and dual monitoring and control on the upper computer end;

13. The device adopts dual screen data synchronization display, which is intuitive and convenient;

14. Cloud based development system, which can be operated through an APP on mobile devices, as well as cloud data storage; Easy to use;